Renal vitamin D receptor expression and vitamin D renoprotection.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 22543902.
- Also identified by DOI 10.1038/ki.2012.30.
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Abstract
Therapy to enhance the renoprotective actions of vitamin D receptor (VDR) activation should safely overcome the distinct VDR content along the nephron to effectively control renal calcium reabsorption, control renal klotho levels for the phosphaturic actions of FGF23, and inhibit proteinuria and the activation of the renin-angiotensin system.
Medical subject headings
- Kidney
- Receptors, Calcitriol