High-throughput immunoassay through in-channel microfluidic patterning.

Zheng, Chunhong; Wang, Jingwen; Pang, Yuhong; Wang, Jianbin; Li, Wenbin; Ge, Zigang; Huang, Yanyi · Lab Chip · 2012

basic_science · Level V

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Abstract

We have developed an integrated microfluidic immunoassay chip for high-throughput sandwich immunoassay tests. The chip creates an array of reactive patterns through mechanical protection by actuating monolithically embedded button valves. We have demonstrated that this chip can achieve highly sensitive immunoassay tests within an hour, and requires only microliter samples.

Medical subject headings