PSA lo and behold: prostate cancer stem cells.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 22560068.
- Also identified by DOI 10.1016/j.stem.2012.04.014.
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Abstract
Human prostate cancers contain multiple cell populations marked by varying levels of the differentiation marker prostate-specific antigen (PSA). In this issue of Cell Stem Cell, Qin et al. (2012) show that PSA(-/lo) cells are enriched for cells with tumor-initiating characteristics and may participate in resistance to androgen-ablative therapies.