Collagen of the dystrophic hamster diaphragm.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 2256018.
- Also identified by PMC identifier 462787.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The collagen content of the diaphragm was measured in normal and dystrophic hamsters aged 130 and 270 days. The diaphragm collagen content was greater in dystrophic hamsters than in control hamsters of the same age. The effect was greater in the older hamsters whether the collagen content was expressed in terms of the percentage of dry weight, in relation to surface area, or as total collagen. This increase was apparently at the expense of muscle tissue and may be a major factor contributing to respiratory muscle weakness as dystrophy advances.
Medical subject headings
- Collagen
- Diaphragm
- Muscular Dystrophy, Animal