Omega 3 fatty acids and GPR120.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22560206.
- Also identified by DOI 10.1016/j.cmet.2012.04.009 and PMC identifier 3803996.
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Abstract
Human loss-of-function gene variants in GPR120 have recently been identified that confer increased risk for obesity and metabolic syndrome. In addition, GPR120 KO mice develop obesity, increased inflammation, and insulin resistance, consistent with a role for GPR120 signaling in the metabolic syndrome and diabetes mellitus.
Medical subject headings
- Fatty Acids, Omega-3
- Insulin Resistance
- Receptors, G-Protein-Coupled