The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22560209.
- Also identified by DOI 10.1016/j.cmet.2012.03.004 and PMC identifier 3767424.
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Abstract
Excessive deposition of fat in the liver (hepatic steatosis) is frequently accompanied by hepatic insulin resistance. Whether this correlation is due to a causal relationship between the conditions has been the subject of considerable debate, and the literature abounds with conflicting data and theories. Here we provide a perspective by defining the problem and its challenges, analyzing the possible causative relationships, and drawing some conclusions.
Medical subject headings
- Fatty Liver
- Insulin
- Insulin Resistance
- Liver