Protective inflammasome activation in AMD.
editorial · Level V
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- Record sourced from PubMed, PMID 22561819.
- Also identified by DOI 10.1038/nm.2761 and PMC identifier 3687521.
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Abstract
Age-related macular degeneration (AMD) is the most common cause of blindness in the elderly. AMD progression is associated with alterations in inflammatory pathways and the immune system. A new study identifies a protective role for inflammasomes in AMD, suggesting that inflammasome activation might be manipulated as a potential therapeutic strategy for this condition (pages 791-798).
Medical subject headings
- Carrier Proteins
- Interleukin-18
- Macular Degeneration
- Optic Disk Drusen