Glass/PDMS hybrid microfluidic device integrating vertically aligned SWCNTs to ultrasensitive electrochemical determinations.

Moraes, Fernando Cruz; Lima, Renato Sousa; Segato, Thiago Pinotti; Cesarino, Ivana; Cetino, Jhanisus Leonel Melendez; Machado, Sergio Antonio Spinola; Gomez, Frank; Carrilho, Emanuel · Lab Chip · 2012

basic_science · Level V

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Abstract

This communication reports a promising platform for rapid, simple, direct, and ultrasensitive determination of serotonin. The method is related to integration of vertically aligned single-walled carbon nanotubes (SWCNTs) in electrochemical microfluidic devices. The required microfabrication protocol is simple and fast. In addition, the nanomaterial influenced remarkably the obtained limit-of-detection (LOD) values. Our system achieved a LOD of 0.2 nmol L(-1) for serotonin, to the best of our knowledge one of the lowest values reported in the literature.