Real-time stochastic detection of multiple neurotransmitters with a protein nanopore.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22616662.
- Also identified by DOI 10.1021/nn301125y.
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Abstract
The detection of several different neurotransmitters with the same sensor in real-time would be a powerful asset to the field of neurochemistry. We have developed a detector for a broad range of neurotransmitters including amino acids, catecholamines, and nucleotides, which relies on the reversible binding of the analytes to a copper(II) complex within an engineered protein nanopore.
Medical subject headings
- Biosensing Techniques
- Conductometry
- Copper
- Nanoparticles
- Neurotransmitter Agents
- Protein Interaction Mapping