Laryngeal stenosis in a patient with severe congenital neutropenia.

Abstract

We report the first case of laryngeal stenosis with granuloma in a patient with severe congenital neutropenia (SCN). Case report and retrospective review. Review of medical records. A 6-year-old female who was diagnosed with SCN presented with a cough and wheezing. An endoscopic study revealed laryngeal stenosis with granuloma. Tracheotomy and direct laryngoscopy were performed under general anesthesia, and administration of granulocyte colony-stimulating factor was started. The laryngeal granuloma disappeared 3 weeks later, and the tracheal stoma was closed. Presence of a laryngeal lesion should be considered in SCN patients with persistent airway symptoms.