Gall-bladder perforation after long-term dapsone therapy.
case_report · Level V
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- Record sourced from PubMed, PMID 2266352.
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Abstract
A 65-year-old man on maintenance dapsone therapy for dermatitis herpetiformis for 30 years was admitted to hospital with acute abdominal pain and vomiting. Investigations revealed a Heinz body haemolytic anaemia. Worsening symptoms prompted an emergency laparotomy that revealed a perforated gall bladder with pigmented biliary calculi. In previous reviews of the haematological abnormalities associated with dapsone therapy, life-threatening cholecystitis has not been described.
Medical subject headings
- Cholecystitis
- Dapsone
- Dermatitis Herpetiformis