Platelet monoamine oxidase B activity in parkinsonian patients.
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- Record sourced from PubMed, PMID 2266365.
- Also identified by PMC identifier 488245.
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Abstract
Monoamine oxidase B (MAO B) plays a pivotal role in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced Parkinsonism. An increased MAO B activity in platelets of patients with idiopathic Parkinson's disease (PD) is reported in this study. The possibility that high MAO B activity may represent a trait of vulnerability for PD by enhancing the neurotoxic effects of environmental compounds is discussed.
Medical subject headings
- Blood Platelets
- Isoenzymes
- Monoamine Oxidase
- Parkinson Disease