Separation of nanoparticles in aqueous multiphase systems through centrifugation.
basic_science · Level V
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- Record sourced from PubMed, PMID 22668343.
- Also identified by DOI 10.1021/nl301452x.
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Abstract
This paper demonstrates the use of aqueous multiphase systems (MuPSs) as media for rate-zonal centrifugation to separate nanoparticles of different shapes and sizes. The properties of MuPSs do not change with time or during centrifugation; this stability facilitates sample collection after separation. A three-phase system demonstrates the separation of the reaction products (nanorods, nanospheres, and large particles) of a synthesis of gold nanorods, and enriches the nanorods from 48 to 99% in less than ten minutes using a benchtop centrifuge.