Getting RNA and protein in phase.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22682242.
- Also identified by DOI 10.1016/j.cell.2012.05.022.
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Abstract
Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but the molecular details of their assembly are poorly understood. Several recent papers identify structural features that drive granule assembly, shedding light on how phase transitions functionally organize the cell and may lead to pathological protein aggregation.
Medical subject headings
- Proteins
- RNA
- Ribonucleoproteins