Stable functionalization of small semiconducting polymer dots via covalent cross-linking and their application for specific cellular imaging.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22684783.
- Also identified by DOI 10.1002/adma.201201245 and PMC identifier 3433747.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A facile cross-linking strategy covalently links functional molecules to semiconducting polymer dots (Pdots) while simultaneously providing functional groups for biomolecular conjugation. In addition to greatly enhanced stability, the formed Pdots are small (<10 nm), which can be difficult to achieve with current methods but is highly desirable for most biological applications. These characteristics are significant for improving labeling efficiency and sensitivity in cellular assays that employ Pdots.
Medical subject headings
- Maleates
- Molecular Imaging
- Polystyrenes
- Semiconductors