Molecular engineered super-nanodevices: smart and safe delivery of potent drugs into tumors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22689222.
- Also identified by DOI 10.1002/adma.201200954.
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Abstract
A super-nanodevice engineered at molecular level integrates various desired properties in a smart and coordinated way, and can "switch on" or "turn off" certain functionalities as required. Importantly, it can break through complex physiological barriers, and then precisely ferry potent toxic triptolide into tumor cells in vivo, thus significantly maximizing the therapeutic efficacy and reducing the drug toxicity.
Medical subject headings
- Antineoplastic Agents
- Drug Carriers
- Nanotechnology
- Neoplasms