Core-shell nanocapsules stabilized by single-component polymer and nanoparticles for magneto-chemotherapy/hyperthermia with multiple drugs.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22689346.
- Also identified by DOI 10.1002/adma.201201251.
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Abstract
Iron-oxide-containing double emulsion capsules carrying both hydrophilic and hydrophobic therapeutic molecules can deliver drugs and energy on demand in vivo. Magneto-chemotherapy/hyperthermia involves a burst-like release of hydrophilic doxorubicin and hydrophobic paclitaxel, remotely triggered by a high frequency magnetic field, which also releases energy via internalized iron oxide nanoparticles, all contributing to cell kill.
Medical subject headings
- Antineoplastic Agents
- Nanocapsules
- Nanoparticles
- Neoplasms
- Polymers