Modeling brain disease in a dish: really?

Marchetto, Maria C; Gage, Fred H · Cell Stem Cell · 2012

basic_science · Level V

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Abstract

Cellular programming and reprogramming technology (CPART) presents a novel approach for understanding disease progression and mechanism. In addition, CPART provides an innovative opportunity for developing diagnostic tools and novel drug candidates for therapy. In this Forum, we will discuss obstacles and solutions for modeling brain disease using CPART.

Medical subject headings