Restoring stem cell function in aged tissues by direct reprogramming?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22704502.
- Also identified by DOI 10.1016/j.stem.2012.04.010.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Adult stem cells are responsible for the cellular turnover of many organs, and an impairment in their function leads to aging and disease. In efforts to reverse the process of tissue stem cell aging, we speculate on the promise and challenges of in vivo direct reprogramming strategies.
Medical subject headings
- Adult Stem Cells
- Cellular Senescence
- Regenerative Medicine