Expanding the boundaries of embryonic stem cells.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22704506.
- Also identified by DOI 10.1016/j.stem.2012.05.003.
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Abstract
The boundaries of embryonic stem cell (ESC) research have extended considerably in recent years in several important ways. Alongside a deeper understanding of the pluripotent state, ESCs have been successfully integrated into various fields, such as genomics, epigenetics, and disease modeling. Significant progress in cell fate control has pushed directed differentiation and tissue engineering further than ever before and promoted clinical trials. The geographical distribution of research activity has also expanded, especially for human ESCs. This review outlines these developments and future challenges that remain.
Medical subject headings
- Cell Differentiation
- Embryonic Stem Cells