The quest for self-identity: not all cancer stem cells are the same.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22711710.
- Also identified by DOI 10.1158/1078-0432.CCR-12-1456 and PMC identifier 3389128.
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Abstract
A central critique of the cancer stem cell (CSC) hypothesis involves the robustness of CSC markers. Zorniak and colleagues suggest that different progenitor marker profiles can classify CSCs, and improved modeling of cellular hierarchies can be achieved by incorporating inter- and intratumoral diversity.
Medical subject headings
- Biomarkers, Tumor
- Brain Neoplasms
- Gene Expression
- Glioblastoma
- Phosphoric Diester Hydrolases