Tumorigenesis. Better by half.
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- Record sourced from PubMed, PMID 22722395.
- Also identified by DOI 10.1038/nrc3307.
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Abstract
This paper suggests that recurrent regions of somatic hemizygosity might exist in tumours because they enable a reduction in the expression levels of genes that restrict cell proliferation and survival, and minimize the loss of genes that are essential for cell survival.