Rewriting the epigenome.
basic_science · Level V
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- Record sourced from PubMed, PMID 22726428.
- Also identified by DOI 10.1016/j.cell.2012.06.008.
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Abstract
The eukaryotic genome is packaged into a highly ordered chromatin structure, with specific domains regulating the transcription patterns of local genes. Hathaway et al. now present a breakthrough technique in the artificial induction of chromatin marks and use this experimental model to test the properties of an induced heterochromatic domain.