Genetic variation in B cell-activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects.

Kumar, Rajesh; Williams, L Keoki; Kato, Atsushi; Peterson, Edward L; Favoreto, Silvio; Hulse, Katie; Wang, Deli; Beckman, Kenneth et al. · J Allergy Clin Immunol · 2012

Level V

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Abstract

A BAFF polymorphism is associated with asthma exacerbations and serum BAFF levels. BAFF expression in vivo increases in natural rhinovirus infection. BAFF may play a role in airway antiviral immunity and impact asthma exacerbation rates.

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