Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22744954.
- Also identified by DOI 10.1002/adma.201201019 and PMC identifier 3668976.
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Abstract
The development of non-toxic quantum dots and further investigation of their composition-dependent cytotoxicity in a high-throughput manner have been critical challenges for biomedical imaging and gene delivery. Herein, we report a rapid sonochemical synthetic methodology for generating a library of highly biocompatible ZnS-AgInS(2) (ZAIS) quantum dots for cellular imaging and siRNA delivery.
Medical subject headings
- Drug Carriers
- Quantum Dots
- RNA, Small Interfering