Regulatory T cells expressing PPAR-γ control inflammation in obesity.
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- Record sourced from PubMed, PMID 22768833.
- Also identified by DOI 10.1016/j.cmet.2012.06.007.
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Abstract
A recent study (Cipolletta et al., 2012) shows that regulatory T (Treg) cells expressing the peroxisome-proliferator- activated receptor (PPAR-γ) are engaged in suppressing adipose tissue inflammation in obesity, suggesting that Treg cells may be a target for treatment and prevention of adipose tissue inflammation and insulin resistance.