Triploidy arising from a first meiotic non-disjunction in a mother carrying a reciprocal translocation.

Abstract

We report on a 22 year old mother, a carrier of a 6;14 balanced reciprocal translocation, who aborted a triploid conceptus carrying a similar translocation. We showed the maternal origin of this triploidy, after non-disjunction at meiosis I. The phenotypic expression as a non-molar pregnancy, the contribution of the maternal translocation, and possible aetiological factors of triploidy are discussed.