Rapid fabrication of complex 3D extracellular microenvironments by dynamic optical projection stereolithography.
basic_science · Level V
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- Record sourced from PubMed, PMID 22786787.
- Also identified by DOI 10.1002/adma.201202024 and PMC identifier 3789064.
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Abstract
The topographic features of the extracelluar matrix (ECM) lay the foundation for cellular behavior. A novel biofabrication method using a digital-mirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated. This robust and versatile platform can generate complex biomimetic scaffolds within seconds. Such 3D scaffolds have promising potentials for studying cell interactions with microenvironments in vitro and in vivo.
Medical subject headings
- Extracellular Matrix