HIV treatment as prevention: debate and commentary--will early infection compromise treatment-as-prevention strategies?

Cohen, Myron S; Dye, Christopher; Fraser, Christophe; Miller, William C; Powers, Kimberly A; Williams, Brian G · PLoS Med · 2012

expert_opinion · Level V

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Abstract

Universal HIV testing and immediate antiretroviral therapy for infected individuals has been proposed as a way of reducing the transmission of HIV and thereby bringing the HIV epidemic under control. It is unclear whether transmission during early HIV infection--before individuals are likely to have been diagnosed with HIV and started on antiretroviral therapy--will compromise the effectiveness of treatment as prevention. This article presents two opposing viewpoints by Powers, Miller, and Cohen, and Williams and Dye, followed by a commentary by Fraser.

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