Liquid viruses by nanoscale engineering of capsid surfaces.

Patil, Avinash J; McGrath, Nina; Barclay, J Elaine; Evans, David J; Cölfen, Helmut; Manners, Ian; Perriman, Adam W; Mann, Stephen · Adv Mater · 2012

basic_science · Level V

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Abstract

Surface engineering of plant virus capsids via cationization (1) and stoichiometric coupling of a polymer surfactant coronal layer (2) produces a highly concentrated, solvent-free liquid virus at 28 °C. These ionic bionanoconstructs are viscoelastic, retain plant infectivity and can be dispersed in a range of organic solvents for aerosol delivery.

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