Immunoglobulin deficiencies: the B-lymphocyte side of DiGeorge Syndrome.
Where this comes from
- Record sourced from PubMed, PMID 22809661.
- Also identified by DOI 10.1016/j.jpeds.2012.06.018.
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Abstract
DiGeorge syndrome is associated with a T-lymphocyte immunodeficiency. The prevalence of hypogammaglobulinemia has not been reported. We found that 3% of patients with DiGeorge syndrome were receiving immunoglobulin replacement therapy and 6% of patients over the age of 3 years had hypogammaglobulinemia. We conclude that DiGeorge syndrome is associated with significant humoral immune deficiency.
Medical subject headings
- B-Lymphocytes
- DiGeorge Syndrome
- IgA Deficiency