Single-cell electroporation using a multifunctional pipette.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22810424.
- Also identified by DOI 10.1039/c2lc40563f and PMC identifier 3805499.
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Abstract
We present here a novel platform combination, using a multifunctional pipette to individually electroporate single-cells and to locally deliver an analyte, while in their culture environment. We demonstrate a method to fabricate low-resistance metallic electrodes into a PDMS pipette, followed by characterization of its effectiveness, benefits and limits in comparison with an external carbon microelectrode.
Medical subject headings
- Electroporation
- Microfluidic Analytical Techniques
- Single-Cell Analysis