Co-factor-enhanced food allergy.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 22845005.
- Also identified by DOI 10.1111/j.1398-9995.2012.02877.x..
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Abstract
Alcohol, exercise or non-steroidal anti-inflamatory drugs (NSAID) are frequently mentioned as amplifiers of food allergic reactions but only individual cases or small series have been previously published. Descriptive study including 74 cases of suspected co-factor enhanced food allergy, assessed by skin-prick tests, specific IgE and oral challenges. Anaphylaxis accounted for 85.1% of reactions. In 99% of cases culprit food allergens were plant-derived, mainly vegetables and cereals. NSAID were involved in 58%, exercise in 52.7% and alcohol in 12.2%. Lipid transfer protein was the most frequently involved allergen. Co-factor enhanced food allergy should be considered when assessing food, alcohol, exercise and NSAID allergic reactions.
Medical subject headings
- Allergens
- Anaphylaxis
- Anti-Inflammatory Agents, Non-Steroidal
- Exercise
- Food Hypersensitivity
- Plant Proteins