A case of cerebrotendinous xanthomatosis. II: The sterol content of a cataractous lens.
case_report · Level V
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- Record sourced from PubMed, PMID 2285688.
- Also identified by PMC identifier 1042235.
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Abstract
The cholestanol content of a cataractous lens nucleus from a patient with cerebrotendinous xanthomatosis (CTX) was quantified by gas chromatography-mass spectrometry and found to be 0.27 micrograms per mg freeze-dried lens tissue. The cholestanol-cholesterol ratio of 1.7% in the lens nucleus was similar to that in the serum of the CTX patient. The cholestanol content and cholestanol-cholesterol ratio in the CTX lens were approximately four-fold and six-fold greater respectively than the mean levels found in three senile cataractous lens nuclei analysed simultaneously for comparative purposes.
Medical subject headings
- Cataract
- Cholestanol
- Lens Nucleus, Crystalline
- Xanthomatosis