Might cigarettes be a "smoking gun" to reduce taxane myelotoxicity?
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 22859717.
- Also identified by DOI 10.1158/1078-0432.CCR-12-1713 and PMC identifier 3440763.
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Abstract
de Graan and colleagues report a retrospective study of the effects of cigarette smoking on taxane pharmacokinetics and myelosuppression. There was no difference in taxane pharmacokinetic clearance between smokers and nonsmokers. Further prospective studies of the effects of cigarette smoking on myelosuppression would be of interest.
Medical subject headings
- Biomarkers, Tumor
- Clinical Trials, Phase II as Topic
- Molecular Targeted Therapy
- Neoplasms
- Randomized Controlled Trials as Topic