Greasing the way: the ABCs of HSPC efflux from the marrow.
editorial · Level V
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- Record sourced from PubMed, PMID 22862939.
- Also identified by DOI 10.1016/j.stem.2012.07.009 and PMC identifier 3429340.
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Abstract
In this issue of Cell Stem Cell, Westerterp et al. demonstrate that cholesterol flux through splenic phagocytes regulates hematopoietic stem and multipotential progenitor cell mobilization from the bone marrow. These exciting findings suggest new avenues for therapy of myeloproliferative disorders and atherosclerosis.