Nine lives for TH9s?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 22869182.
- Also identified by DOI 10.1038/nm.2868 and PMC identifier 6352967.
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Abstract
There is currently much interest in dissecting the mechanisms of tumor immunity. A new study shows that a subset of CD4<sup>+</sup> T cells that produce the cytokine interleukin-9 (IL-9) mediate inhibition of melanoma growth in mice and that analogous IL-9-producing T cells are present in human skin (pages 1248–1253). Could such cells be manipulated to develop new therapeutic strategies for melanoma?
Medical subject headings
- CD4-Positive T-Lymphocytes
- Melanoma, Experimental