Symptomatic infection and detection of vaccine and vaccine-reassortant rotavirus strains in 5 children: a case series.
case_series · Level IV
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- Record sourced from PubMed, PMID 22872730.
- Also identified by PMC identifier 4618559.
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Abstract
Vaccine or vaccine-reassortant rotavirus strains were detected in fecal specimens from 5 of 106 (4.7%) immunocompetent children who required treatment for rotavirus gastroenteritis at a large pediatric hospital in Texas in 2009-2010. Four strains were related to pentavalent rotavirus vaccine, whereas one was related to monovalent rotavirus vaccine. The contribution of these strains to each patient's illness was unclear given that 2 patients had prominent respiratory symptoms and 2 were concurrently infected with another pathogen (group F adenovirus and norovirus). Continued monitoring is necessary to assess the role of vaccine strains and vaccine-reassortant strains in pediatric rotavirus infections.
Medical subject headings
- Reassortant Viruses
- Rotavirus
- Rotavirus Infections
- Rotavirus Vaccines