Nutropioids, hedonism in the gut?
Where this comes from
- Record sourced from PubMed, PMID 22883226.
- Also identified by DOI 10.1016/j.cmet.2012.07.011.
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Abstract
The opioid system plays a pivotal role in how our brain regulates hedonic components of ingestive behavior. Duraffourd et al. (2012) add the gut to this opioid landscape, demonstrating direct activation of periportal μ-opioid receptors by food-derived opioid peptides (nutropioids), and a gut-brain feedback spiral that culminates in enhanced satiety.