Contraception for men: a breakthrough new approach.
basic_science · Level V
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- Record sourced from PubMed, PMID 22901799.
- Also identified by DOI 10.1016/j.cell.2012.07.027 and PMC identifier 4388035.
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Abstract
There has not been a new reversible contraceptive for men since the development of the condom, centuries ago. Matzuk et al. describe a new molecular approach using administration of a small molecule to directly and reversibly inhibit spermatogenesis in mice by blocking the function of a testicular bromodomain without apparent adverse effect on the organism or offspring.