Poxvirus use a "gene accordion" to tune out host defenses.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22901801.
- Also identified by DOI 10.1016/j.cell.2012.07.026.
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Abstract
A multistep process of gene amplification, mutation, and reduction allows poxvirus to overcome host antiviral defenses. The mechanism speeds genetic adaptation and promises to be broadly applicable in many biological settings.