The power of negative thinking: which cells limit tumor immunity?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22912390.
- Also identified by DOI 10.1158/1078-0432.CCR-12-2418.
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Abstract
Why human tumors grow infiltrated by specific antitumor T cells has been a mystery attributed to negative factors released directly by the tumor or indirectly through immune intermediaries. The frequency and phenotype of myeloid-derived suppressor cells in the peripheral blood of melanoma patients and healthy donors are surprisingly similar.
Medical subject headings
- Melanoma
- Myeloid Cells
- Skin Neoplasms
- T-Lymphocytes