Quantitative biology of single neurons.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22915636.
- Also identified by DOI 10.1098/rsif.2012.0417 and PMC identifier 3481569.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The building blocks of complex biological systems are single cells. Fundamental insights gained from single-cell analysis promise to provide the framework for understanding normal biological systems development as well as the limits on systems/cellular ability to respond to disease. The interplay of cells to create functional systems is not well understood. Until recently, the study of single cells has concentrated primarily on morphological and physiological characterization. With the application of new highly sensitive molecular and genomic technologies, the quantitative biochemistry of single cells is now accessible.
Medical subject headings
- Neurons
- Single-Cell Analysis