Science to practice: can macrophage infiltration serve as a surrogate marker for stem cell viability?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22919033.
- Also identified by DOI 10.1148/radiol.12121378.
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Abstract
Following in vivo prelabeling of host macrophages with ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles, it was shown that their magnetic resonance (MR) imaging–visible migration into knee implants of scaffolded adipose-derived stem cells (ADSCs) undergoing apoptosis can serve as a surrogate marker of stem cell death.
Medical subject headings
- Dextrans
- Macrophage Activation
- Macrophages
- Magnetic Resonance Imaging
- Stem Cell Transplantation