Chemically functionalized water-soluble single-walled carbon nanotubes modulate morpho-functional characteristics of astrocytes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22924813.
- Also identified by DOI 10.1021/nl302178s.
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Abstract
We report the use of chemically functionalized water-soluble single-walled carbon nanotubes (ws-SWCNTs) for the modulation of morpho-functional characteristics of astrocytes. When added to the culturing medium, ws-SWCNTs were able to make astrocytes larger and stellate/mature, changes associated with the increase in glial fibrillary acidic protein immunoreactivity. Thus, ws-SWCNTs could have more beneficial effects at the injury site than previously thought; by affecting astrocytes, they could provide for a more comprehensive re-establishment of the brain computational power.
Medical subject headings
- Astrocytes
- Nanotubes, Carbon
- Water