Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22936170.
- Also identified by DOI 10.1038/nmeth.2114 and PMC identifier 3477589.
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Abstract
We discuss unique features of lens-free computational imaging tools and report some of their emerging results for wide-field on-chip microscopy, such as the achievement of a numerical aperture (NA) of ∼0.8-0.9 across a field of view (FOV) of more than 20 mm(2) or an NA of ∼0.1 across a FOV of ∼18 cm(2), which corresponds to an image with more than 1.5 gigapixels. We also discuss the current challenges that these computational on-chip microscopes face, shedding light on their future directions and applications.
Medical subject headings
- Image Processing, Computer-Assisted
- Microscopy