Erythroid 5-aminolevulinate synthase is located on the X chromosome.
basic_science · Level V
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- Record sourced from PubMed, PMID 2294742.
- Also identified by PMC identifier 1683546.
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Abstract
The gene for erythroid 5-aminolevulinate synthase has been mapped to Xpter-Xq26 by Southern blot hybridization analysis of a mouse/human hybrid cell panel. In situ hybridization maps the gene to Xp21-Xq21, with the most likely location being on band Xp11.2. The mapping of the erythroid 5-amino-levulinate synthase gene to the X chromosome suggests that a defect in this gene may be the primary cause of X-linked sideroblastic anemia.
Medical subject headings
- 5-Aminolevulinate Synthetase
- Erythrocytes
- X Chromosome