Measurement of barrier tissue integrity with an organic electrochemical transistor.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22949380.
- Also identified by DOI 10.1002/adma.201202612.
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Abstract
The integration of an organic electrochemical transistor with human barrier tissue cells provides a novel method for assessing toxicology of compounds in vitro. Minute variations in paracellular ionic flux induced by toxic compounds are measured in real time, with unprecedented temporal resolution and extreme sensitivity.
Medical subject headings
- Biological Assay
- Biosensing Techniques
- Cell Survival
- Ethanol
- Hydrogen Peroxide
- Transistors, Electronic