Structural biology: A protein engagement RING.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22955611.
- Also identified by DOI 10.1038/489043a and PMC identifier PMC2859195.
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Abstract
The mechanistic details of the attachment of a small protein, ubiquitin, to other proteins are unclear. Crystal structures of the E2–ubiquitin and RING E3 enzymes, engaged and ready for transfer, provide fresh insights.