The nexus of Aβ, aging, and sleep.

Gerstner, Jason R; Perron, Isaac J; Pack, Allan I · Sci Transl Med · 2012

editorial · Level V

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Abstract

Roh et al. report a positive feedback loop between sleep-wake irregularities and aggregation of β-amyloid peptide, suggesting that sleep alterations could be an early event in Alzheimer's disease.

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